Polycystic Ovary Syndrome (PCOS) is a common hormonal condition linked to insulin resistance and chronic inflammation. This creates a vicious cycle — hormonal imbalance worsens metabolism, while inflammation makes symptoms like weight gain, acne, and irregular periods harder to manage.
To break this cycle, a balanced medical and nutritional approach is essential.
At
Dr. Lakhe’s Healthcare Centre, Kharadi, Pune,
Dr. Mahesh Lakhe focuses on evidence-based strategies to restore hormonal and metabolic health in women with PCOS.
🧬 What the Latest Research Reveals
A 2025 study published in Lipids in Health and Disease explored whether ketogenic diets (KDs) could disrupt this vicious cycle by comparing them with other high-fat diets.
The findings highlight that a clinically supervised ketogenic diet can:
✅ Improve insulin sensitivity
✅ Reduce systemic inflammation
✅ Support weight loss
✅ Lower androgen levels (linked to acne and excess hair growth)
✅ Promote menstrual regularity and fertility
🍳 How the Ketogenic Diet Works in PCOS
| Mechanism |
Effect on PCOS |
Research Insight |
| Anti-inflammatory effect of β-hydroxybutyrate (BHB) |
Reduces NLRP3 inflammasome activation → less inflammation |
Helps restore insulin sensitivity |
| Better insulin control |
Lower insulin = reduced ovarian androgen production |
Leads to regular cycles & improved fertility |
| Gut microbiome balance |
KD alters gut bacteria composition |
Supports improved metabolism |
| Reduced visceral fat |
Decreases pro-inflammatory adipokines |
Enhances hormonal balance |
⚠️ When to Avoid a Ketogenic Diet
A ketogenic diet should not be started without medical advice, especially if you are:
- Pregnant or breastfeeding
- Living with type 1 diabetes
- Having kidney, liver, or heart conditions
- Prone to nutritional deficiencies
At our centre, Dr. Lakhe monitors all patients closely to ensure safe and effective outcomes.
Dr. Lakhe’s Clinical Perspective
At Dr. Lakhe’s Healthcare Centre, the focus is on restoring long-term metabolic balance- not just controlling PCOS symptoms.
Dr. Mahesh Lakhe emphasizes that a medically supervised ketogenic diet can improve metabolism and hormones, but must be tailored and monitored for safety.
The clinic offers complete metabolic evaluations, personalized ketogenic programs with guided transitions to balanced diets, and essential nutrient support to ensure safe, lasting results.
In Summary
The 2025 research highlights that a medically guided ketogenic diet can be a valuable tool in managing PCOS- by breaking the cycle of inflammation, insulin resistance, and hormonal imbalance.
At
Dr. Lakhe’s Healthcare Centre, Kharadi, we design individualized plans to ensure that every patient finds the right nutritional and lifestyle path toward balance and wellbeing.
If you’re struggling with PCOS, weight gain, or hormonal issues, consult
Dr. Mahesh Lakhe today to explore a customized, research-backed solution for you.
📍 Visit Us
📞 Book your consultation today and take the first step toward hormonal and metabolic wellness.
